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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADRA1B
All Species:
30
Human Site:
Y144
Identified Species:
66
UniProt:
P35368
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35368
NP_000670.1
520
56836
Y144
C
A
I
S
I
D
R
Y
I
G
V
R
Y
S
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Q28524
418
44639
P92
V
M
G
L
L
V
V
P
P
A
A
T
L
V
L
Dog
Lupus familis
XP_536449
618
67286
Y144
C
A
I
S
I
D
R
Y
I
G
V
R
Y
S
L
Cat
Felis silvestris
Mouse
Mus musculus
P97717
514
56400
Y143
C
A
I
S
I
D
R
Y
I
G
V
R
Y
S
L
Rat
Rattus norvegicus
P15823
515
56567
Y144
C
A
I
S
I
D
R
Y
I
G
V
R
Y
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506393
511
56733
Y146
C
A
I
S
I
D
R
Y
I
G
V
R
Y
S
L
Chicken
Gallus gallus
XP_414483
507
56995
Y148
C
A
I
S
I
D
R
Y
I
G
V
R
Y
S
L
Frog
Xenopus laevis
O42574
385
43291
A59
G
N
I
M
V
I
V
A
I
G
R
N
Q
R
L
Zebra Danio
Brachydanio rerio
XP_001922013
544
60273
Y141
C
V
I
S
I
D
R
Y
I
G
V
R
Y
P
L
Tiger Blowfish
Takifugu rubipres
O42385
423
46982
L97
T
D
L
M
V
S
V
L
V
L
P
M
A
A
L
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203873
574
63580
Y141
C
V
I
S
I
D
R
Y
I
G
V
T
R
P
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
32.1
76.8
N.A.
94.8
94.6
N.A.
77.6
70.9
28
54
25.9
N.A.
N.A.
N.A.
36.2
Protein Similarity:
100
N.A.
46.7
79.1
N.A.
96.3
96.5
N.A.
82.8
78.8
43.4
64.3
42.6
N.A.
N.A.
N.A.
49.6
P-Site Identity:
100
N.A.
6.6
100
N.A.
100
100
N.A.
100
100
26.6
86.6
6.6
N.A.
N.A.
N.A.
73.3
P-Site Similarity:
100
N.A.
13.3
100
N.A.
100
100
N.A.
100
100
33.3
86.6
33.3
N.A.
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
55
0
0
0
0
0
10
0
10
10
0
10
10
0
% A
% Cys:
73
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
73
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
10
0
0
0
0
0
0
82
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
82
0
73
10
0
0
82
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
10
10
10
0
0
10
0
10
0
0
10
0
100
% L
% Met:
0
10
0
19
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
10
0
10
0
0
19
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
73
0
0
0
10
64
10
10
0
% R
% Ser:
0
0
0
73
0
10
0
0
0
0
0
0
0
55
0
% S
% Thr:
10
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% T
% Val:
10
19
0
0
19
10
28
0
10
0
73
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
73
0
0
0
0
64
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _